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Resverlogix Corp T.RVX

Sector: Healthcare | Sub-Sector: Biotechnology
Alternate Symbol(s):  RVXCF

Resverlogix Corp is a clinical stage cardiovascular company. It is engaged in developing RVX-208, a molecule selective inhibit BET domain inhibitor for the treatment of patients with cardiovascular, diabetes mellitus, Alzheimer's & chronic kidney disease.
Price: $1.82 | Change: $0.00 | %Change: 0.00%
Volume: 5,266 | Day High/Low: 1.83/1.77 | 52 Week High/Low: 3.13/0.405
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0 stars

RE:RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Go,not to worry; I am sure DR NICHOLLS will work out a perfect trial as he did in Assure. Just joking! Jk  rate and reply
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RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

toinv/ Bear...As I see it they may have a problem with recruiting patients that would be willing to go on trial if the only condition they are facing is high LDL. Statins are the best-known drug to...read more
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RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Yes Toniv you are 100% correct. To be eligible for BETonMACE patients will be low-HDL, diabetic and on statin at time of screening or will start statin when dosing begins. Additionally, I believe ~15%...read more
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RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Hi GV. Interesting and helpful layout. I guess that is why it takes so much time to get the trial designed. My unerstanding was that the selection is a series of "and" conditions. e.g. They will be...read more
5 stars

RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Of course RVX would like RVX-208 to be prescribed for all of these! Results of BETonMACE and results of the Emerald Logic Facet analysis should be helpful. However, keep in mind that MACE risk is...read more
0 stars

RVX-208 MAY WELL AFFECT FIBRIN CELL REACTION IN DM

FYI: Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which...read more
5 stars

RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

toinv...it would be very beneficial if Resverlogix actually provides specific examples of how RVX-208 will be prescribed for : Patients that have not had an incident but have elevated LDL Patients...read more
5 stars

RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Hi GV. I'm not a science person but here is my understanding. rvx-208 will be prescribed in addition to a statin - specifically Crestor. The reason is that the statin works to reduce LDL (bad...read more
3 stars

RE:RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

It is my impression that very few patients have low HDL and normal LDL. That explains why the company is focused on patients already taking a statin. However, the ultimate market is huge because this...read more
5 stars

RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

No, my point is that it is very unlikely that RVX-208 would ever be prescribed in place of a statin because the two drugs address two distinct risk factors for cardiovascular disease, which are two...read more
5 stars

RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

From my understanding RVX 208 will be combined with Crestor and that is how it will be packaged and approved hopefully by the FDA for standard of care. RVX 208 for Cardio.diabetic will be the combo...read more
1 star

RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Bear to continue with my thought...If I understand you correctly RVX-208 would be a stand-alone drug for the following reasons you stated:  "There is no approved drug for raising HDL. RVX-208 can do...read more
1 star

RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Bear so RVX-208 will always be prescribed with a statin. Is this what you are saying, thereby making it a non-solo drug. G1945V  rate and reply
5 stars

RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

I meant to say "There is incredible residual risk for cardiovascular disease in diabetic patients even after statin treatment. RVX-208 can treat this."  rate and reply
5 stars

RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

RVX-208 is for low-HDL, Statins are for high-LDL. Two completely different drug targets and mostly non-overlapping mechanisms of action. I say mostly because I think statins have been reported to have...read more
3 stars

RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

prince..those are all good questions. I simply don't know how RVX-208 will be prescribed over statins. Will it be prescribed in addition to a statin or instead of? For example, I was not on a statin...read more
0 stars

gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

..so thinking forward, if 208 proves to possess a 27.5% RRR MACE vs. others, in real life would that be meaningful to your doctor or is it a whole range of QoL factors that come into play, knowing i...read more
1 star

250 Events

@ 27.5% RRR 208 105 - SoC 145 Events @ 75% RRR 208 50 - SoC 200 Events... ...IMO those are two very different paradigms, in the 27.5% plan i see a very good difference but IMO QoL of non-MACE...read more
1 star

RE:RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

I've had The identical experience...Crestor took ALL the muscle pains away..:)  rate and reply
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RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

Just a short comment on Lipitor versus Crestor. In my personal experience after taking Lipitor for a number of years my doctor switched me to Crestor a number of Years ago. This was prior to being...read more