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Resverlogix Corp T.RVX

Sector: Healthcare | Sub-Sector: Biotechnology
Alternate Symbol(s):  RVXCF

Resverlogix Corp is a clinical stage cardiovascular company. It is engaged in developing RVX-208, a molecule selective inhibit BET domain inhibitor for the treatment of patients with cardiovascular, diabetes mellitus, Alzheimer's & chronic kidney disease.
Price: $1.82 | Change: $0.00 | %Change: 0.00%
Volume: 5,266 | Day High/Low: 1.83/1.77 | 52 Week High/Low: 3.13/0.405
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3 stars

RE:RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

It is my impression that very few patients have low HDL and normal LDL. That explains why the company is focused on patients already taking a statin. However, the ultimate market is huge because this...read more
5 stars

RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

No, my point is that it is very unlikely that RVX-208 would ever be prescribed in place of a statin because the two drugs address two distinct risk factors for cardiovascular disease, which are two...read more
0 stars

RE:RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

From my understanding RVX 208 will be combined with Crestor and that is how it will be packaged and approved hopefully by the FDA for standard of care. RVX 208 for Cardio.diabetic will be the combo...read more
0 stars

RE:RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Bear to continue with my thought...If I understand you correctly RVX-208 would be a stand-alone drug for the following reasons you stated:  "There is no approved drug for raising HDL. RVX-208 can do...read more
0 stars

RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

Bear so RVX-208 will always be prescribed with a statin. Is this what you are saying, thereby making it a non-solo drug. G1945V  rate and reply
5 stars

RE:RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

I meant to say "There is incredible residual risk for cardiovascular disease in diabetic patients even after statin treatment. RVX-208 can treat this."  rate and reply
5 stars

RE:RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

RVX-208 is for low-HDL, Statins are for high-LDL. Two completely different drug targets and mostly non-overlapping mechanisms of action. I say mostly because I think statins have been reported to have...read more
3 stars

RE:gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

prince..those are all good questions. I simply don't know how RVX-208 will be prescribed over statins. Will it be prescribed in addition to a statin or instead of? For example, I was not on a statin...read more
0 stars

gv...MACE vs. QoL vs. Lipitor-Crestor or 208...

..so thinking forward, if 208 proves to possess a 27.5% RRR MACE vs. others, in real life would that be meaningful to your doctor or is it a whole range of QoL factors that come into play, knowing i...read more
1 star

250 Events

@ 27.5% RRR 208 105 - SoC 145 Events @ 75% RRR 208 50 - SoC 200 Events... ...IMO those are two very different paradigms, in the 27.5% plan i see a very good difference but IMO QoL of non-MACE...read more
1 star

RE:RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

I've had The identical experience...Crestor took ALL the muscle pains away..:)  rate and reply
0 stars

RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

Just a short comment on Lipitor versus Crestor. In my personal experience after taking Lipitor for a number of years my doctor switched me to Crestor a number of Years ago. This was prior to being...read more
1 star

RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

toinv...please do not misunderstand what is being said. There is no suggestion that that anyone would stop taking statins of any brand during the BonM trials for any reason.  What I am saying is that...read more
0 stars

RE:RE:RE:RE:GV, a question of your experience with Lipitor???

Hi GV. I wonder why, in the BETonMACE trial phase lll, anyone would stop taking Crestor? As I understand it the patients will remain on their standard of care treatment (Crestor or Liptitor) and on a...read more
1 star

RE:RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

prince..that explains it.  thx. :)  rate and reply
1 star

RE:RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

gv, you don't want researchers biasing the trial the safety board will know but no one active in the trial should know...at specific point(s) data will be unblinded but mid-trial only for safety...read more
1 star

RE:RE:RE:RE:RE:GV, a question of your experience with Lipitor???

prince ...I know the patients would not know but if the researchers don't know who is taking what how can they conduct the study to see what's what? I am not disputing what you are saying because I...read more
1 star

RE:RE:RE:RE:GV, a question of your experience with Lipitor???

gv, you is wrong, double blind means neither patient nor trial staff know who gets what...only way to tell (like cheating) is by knowing if there are different treatment effects (like x generates a...read more
1 star

RE:RE:RE:GV, a question of your experience with Lipitor???

prince ...yes BonM is double blinded. But  the clinic would certainly know the 4 groups. If I should decide to stop taking Crestor overnight I would not feel any different, however I would need to...read more
1 star

RE:RE:GV, a question of your experience with Lipitor???

gv, isn't this a double blinded trial (ie no body knows who gets assigned exactly to what of the four arms)???? and how long would you before you started to feel "bad" if you stopped taking Crestor???  rate and reply