Unless the fundamentals on a stock change "be right & sit tight" tends to be a good strategy.  RGX has been and will likely continue to be a news driven stock, plus this time of year it is easier to move / manipulate a share price.  I have been buying the dips over the past ~12 months and am happy that my average cost basis has been increasing considering that this stock is up roughly 200% year to date.  If you can stand the volatility and are patient you will do just fine with RGX.  If you can't stand share price volatility (are losing sleep) you might not want to be in a venture stock anyway.....