Top 10 cancer

Breakthroughs of 2011

TORONTOJan. 3, 2012 /CNW/ - The Canadian Cancer Society is proud to announce its top 10 breakthroughs of 2011. This list of accomplishments showcases how researchers funded by the Society continue to lead the way in advances that will reduce the number of Canadians diagnosed with and dying from cancer, and improve the quality of life for people living with and beyond cancer. Due to progress in cancer research, over 60 per cent of Canadians diagnosed with cancer will survive, compared with only 25 per cent when the Society began funding research in the 1940s.

"2011 has been a very exciting year for cancer research," said Sarah Bouma, Senior Manager, Research, Canadian Cancer Society, Ontario Division. "Society funded researchers have made tremendous gains, particularly in clinical trials. Research advances in Ontario and across the country are impacting the lives of people living with cancer, their families and caregivers."

Story highlights include:

  • A landmark clinical trial of a new way to prevent breast cancer.
  • Toronto protocol that gives 100% survival for families with a specific hereditary cancer.
  • The discovery of a human blood stem cell that could end the search for bone marrow.
  • A new imaging method that could detect lung cancer with more accuracy.
  • A clinical trial that has found that men with prostate cancer can take a drug 'holiday'.
  • The development of tumour-killing nanoparticles.

The top 10 breakthroughs are available at http://files.newswire.ca/1012/top10breakthroughs.pdf.

On the link above - please see BREAKTHROUGH #7 

http://verisante.com/news/56/verisante-technology-inc-announces-pilot-study-results-for-lung-cancer-detection-system/

 

Verisante Technology Inc. Announces Pilot Study Results for Lung Cancer Detection System


July 6, 2011 at 7:00 am

Vancouver, Canada: Verisante Technology, Inc. (TSX-V: VRS; OTCQX: VRSEF) (the “Company” or “Verisante”) is pleased to announce that the results of a pilot study on lung cancer detection will be published in the prestigious Journal of Thoracic Oncology in July.  The results of the pilot study indicate that the Company’s system technology could set a new standard for the early detection of lung cancer.

The Company owns, co-owns, or has the exclusive rights to all of the technology used in the pilot study, which was generously funded by the Canadian Institutes of Health Research (“CIHR”) and the Canadian Cancer Society.

Verisante is currently developing a commercial prototype of the laser Raman system, the Verisante Core™, licensed from the BC Cancer Agency which, when combined with the ClearVu™ and ClearVu Elite™ systems recently acquired from Perceptronics Medical Inc., reduces false positives by over 75% compared to current endoscopic methods.  

The ClearVu™ system is a simultaneous white light and fluorescence real time video accessory which is used with a fiberoptic bronchoscope for lung cancer examinations.   The ClearVu Elite™ has the addition of real time reflectance and fluorescence spectral analysis to assess the malignancy potential of suspicious lesions.  The technology is complementary to the Verisante Core™ which uses rapid Raman spectral analysis for the detection of lung cancer.

The principle investigators of the study to be published in the Journal of Thoracic Oncology in July are Dr. Stephen Lam, Chair of the Lung Tumor Group at BC Cancer Agency, and Dr. Haishan Zeng, Senior Scientist at the BC Cancer Agency’s Integrative Oncology Department.

The title and summary of the article are below:

Using Laser Raman Spectroscopy to Reduce False Positives of Autofluorescence Bronchoscopies: A Pilot Study

Preneoplastic lesions of the bronchial tree have a high probability of developing into malignant tumors. Currently, the best method for localizing them for further treatment is a combined white light bronchoscopy (WLB) and autofluorescence bronchoscopy (AFB) (WLB + AFB). The average specificity from large clinical trials for this combined detection method is approximately 60%, leading to many false positives.

A laser Raman Spectroscopy (LRS) system was developed to collect real-time, in vivo lung spectra with a fiber optic catheter passed down the instrument channel of a bronchoscope. WLB + AFB imaging modalities were used to identify lesions from 26 subjects, from which 129 Raman spectra were measured. Multivariate statistical analyses were performed on the spectra with a leave-one-out cross validation.

Clear in vivo Raman spectra were obtained in 1 second.  Preneoplastic lesions were detected with a sensitivity of 96% and a specificity of 91%.

Conclusion: 
Adding point LRS analysis to WLB + AFB imaging has the ability to detect preneoplastic lesions in real time with high sensitivity and specificity. The use of LRS has great potential for substantially reducing the number of false-positive biopsies associated with WLB + AFB with very little reduction in the detection sensitivity.

About the Journal of Thoracic Oncology

The Journal of Thoracic Oncology (“JTO”), the official Journal of the International Association for the Study of Lung Cancer, is the primary educational and informational publication for topics relevant to detection, prevention, diagnosis, and treatment of thoracic malignancies. JTO emphasizes a multidisciplinary approach, and includes original research (clinical trials and translational or basic research), reviews, and opinion pieces. The audience consists of epidemiologists, medical oncologists, radiation oncologists, thoracic surgeons, pulmonary specialists, radiologists, pathologists, and research scientists with a special interest in thoracic oncology.

About Verisante Technology, Inc.

Verisante is a medical device company committed to commercializing innovative systems for the early detection of cancer. The Verisante Aura™ for skin cancer detection and the Verisante Core™ series for lung, colon and cervical cancer detection utilize a proprietary cancer detection platform while the operating software and probe technology are unique to each device. The cancer detection platform was developed by the BC Cancer Agency and tested and refined on approximately 1,000 lesions at the Skin Care Centre at Vancouver General Hospital. This exclusive platform technology allows Verisante to develop and offer a range of compact, non-invasive cancer detection devices that offer physicians’ immediate results for many of the most common cancers.  The Aura and Core have not yet been approved for sale.  The Company anticipates Health Canada approval for the Aura in late 2011.

The TSX Venture Exchange has neither approved nor disapproved of the contents of this press release. Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release. 

For further information contact:

Verisante Technology, Inc.
Thomas Braun, President & CEO    
Telephone: (604) 605-0507

Email: info@verisante.com
Website:  www.verisante.com
Youtube:  www.youtube.com/verisante
Twitter: www.twitter.com/verisante
Facebook: www.facebook.com/verisante

Forward Looking Statements 
This release contains forward-looking statements, including, but not limited to, statements regarding the future commercialization of medical devices, the market demand for these products and the proprietary protections the Company will obtain with regard to the technology, all of which statements are subject to market risks, and the possibility that the Company will not be able to obtain patent protection or obtain sufficient customer demand. These statements are made based upon current expectations and actual results may differ from those projected due to a number of risks and uncertainties. 

 

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